Publications
Selected publications
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
Perier C., Bové J., Wu D.C., Jackson-Lewis V., Dehay B., Choi D.G., Rathke-Hartlieb S, Bouillet P, Strasser A,. Schulz J.B., Przedborski S., and Vila M. Proceedings of the National Academy of Sciences USA (in press)
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage.
Perier C., Tieu K., Guegan C., Caspersen C., Jackson-Lewis V., Carelli V., Martinuzzi A., Hirano M., Przedborski S. and Vila M.
Proceedings of the National Academy of Sciences USA, 102(52):19126-19131 (2005)
Genetic clues to the pathogenesis of Parkinson’s Disease.
Vila M. and Przedborski S.
Nature Medicine, 10 Suppl:S58-62 (2004)
Targeting programmed cell death in neurodegenerative diseases.
Vila M. and Przedborski S.
Nature Reviews Neuroscience, 4(5):365-75 (2003)
Neurodegeneration : what is it and where are we?
Przedborski S., Vila M. and Jackson-Lewis V.
Journal of Clinical Investigation, 111(1):3-10 (2003)
Bax ablation prevents dopaminergic neurodegeneration in the MPTP mouse model of Parkinson´s disease.
Vila M., Jackson-Lewis V., Vukosavic S., Djaldetti R., Liberatore G., Offen D., Korsmeyer SJ and Przedborski S.
Proceedings of the National Academy of Sciences USA, 98(5):2837-2842 (2001)
Engineered modeling and the secrets of Parkinson’s disease.
Vila M., Wu D.C. and Przedborski S.
Trends in Neuroscience, 24(11): S49-S55 (2001)
Time course changes in metabolic and electrophysiologic neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra.
Vila M., Perier C., Feger J., Yelnik J., Faucheux B., Ruberg M., Raisman-Vozari R., Agid Y. and Hirsch E.C.
European Journal of Neuroscience, 12(1):337-344 (2000)
Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and non-human primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA.
Vila M., Levy R., Herrero M.T., Ruberg M., Faucheux B., Obeso J.A., Agid Y. and Hirsch E.C.
Journal of Neuroscience, 17 (2):765-773 (1997)
